Neurobiology Gallery

Juvenile rat cerebral vasculature


Brain vasculature visualized using Contrast Microbubbles
Infusion of contrast microbubbles into the brain microvasculature of a mouse.

Vasculature in the Brain during Ischemic Stroke
Vasculature in the mouse brain, visualized with color Doppler during transient carotid artery occlusion.

Vasculature in the Mouse Brain
Microvasculature in the mouse brain visualized in 4D after contrast microbubble injection.

Lesion in Embryo Spine - Spina Bifida Rat Model

Spina bifida is a neural tube defect that results in incomplete closing of the spinal cord. Spina bifida is associated with abnormalities in the cerebellum and cisterna magna during fetal development. This image acquired using the Vevo 3100.

Embryo Cerebellum - Spina Bifida Rat Model

Spina bifida is a neural tube defect that results in incomplete closing of the spinal cord. Spina bifida is associated with abnormalities in the cerebellum and cisterna magna during fetal development. This image acquired using the Vevo 3100.

Screenshot of mouse brain atlas

Screenshot of the Vevo LAB software displaying several different views of the CD-1 mouse brain atlas which comes with the Vevo BRAIN stereotactic frame.

Neuroanatomy of the mouse brain

3D rendered surface view of the mouse brain segmented by anatomical region based on ex vivo high frequency ultrasound images.

Ischemia/hypoxia stroke model

Plot of oxygen saturation (sO2) over time in the left (pink) and right (orange) cortical and subcortical hemisphere ROIs while restoring breathed oxygen to 100% from 7.5% post ischemia/hypoxia for stroke induction. Ultrasound (top) and photoacoustic (bottom) coronal images in the right panel show a frame of mouse brain post ischemia/hypoxia. The red, white and blue color represents a parametric map of oxygen saturation. The right hemisphere does not fully recover sO2 levels post-reperfusion/normoxia that are shown in the left hemisphere, indicating a cerebral infarct, especially in cortical and subcortical areas.

Ischemia/hypoxia stroke model

Ultrasound (left) and photoacoustic (right) coronal images of a mouse brain post ischemia/hypoxia. The red, white and blue color represents a parametric map of oxygen saturation. The right hemisphere does not fully recover sO2 levels post-reperfusion/normoxia that are shown in the left hemisphere, indicating a cerebral infarct, especially in cortical and subcortical areas.

Blood flow in the neonatal rat brain

3D rendered color Doppler (red and blue) and ultrasound (greyscale) coronal image showing direction and velocity of blood flow in the neonatal rat brain.

Ischemia/hypoxia stroke model

3D rendered coronal ultrasound (greyscale) and photoacoustic (red) images of a mouse brain during ligation of the right common carotid artery. The red color represents higher oxygen saturation clearly showing lower sO2 in the right hemisphere.

Blood flow in the mouse head

3D rendered color Doppler (red and blue) C-scan image showing direction and velocity of blood flow in the mouse brain and surrounding structures.

Oxygen saturation map in the mouse brain

3D rendered co-registered ultrasound (greyscale) and photoacoustic (red and white) image showing a parametric map of oxygen saturation with red signals indicating higher sO2 values.

Ischemia/hypoxia stroke model

Co-registered 3D rendered ultrasound (greyscale) and color Doppler (red and blue) coronal image of a mouse brain during ligation of the right common carotid artery. The red and blue color represent blood flow velocity and direction clearly showing impaired blood flow in the right hemisphere.

Blood signal in mouse brain

3D rendered photoacoustic image showing cerebral blood signal in the mouse brain.

Ischemia/hypoxia stroke model

Ultrasound (top) and photoacoustic (bottom) coronal images of a mouse brain during ligation of the right common carotid artery. The red, white and blue color represents a parametric map of oxygen saturation clearly showing lower sO2 in the right hemisphere.

Mouse brain transverse section

High-resolution 3D ultrasound image of a transverse section of an excised CD-1 mouse brain at 40MHz. Such images are used in the Vevo BRAIN anatomical atlas.

Mouse brain coronal section

High-resolution ultrasound image of a coronal section of an excised CD-1 mouse brain at 40MHz. Such images are used in the Vevo BRAIN anatomical atlas. Learn more about neuroimaging in vivo.

Oxygen saturation map in the mouse brain

3D rendered co-registered ultrasound (greyscale) and photoacoustic (red, white and teal) image showing a parametric map of oxygen saturation with red signals indicating higher sO2 values.

Ischemia induction in the mouse brain
Live ultrasound (left) and photoacoustic (right) coronal section of a mouse brain during ligation of the right common carotid artery. The red, white and blue color represents a parametric map of oxygen saturation clearly showing the drop in sO2 in the right hemisphere upon ligation.