4D-Mode Imaging
Seeing More Matters - Capture the Entire Heart in Motion!
Bringing Together Dynamic Motion and 3D Geometry!
Quantify ejection fraction and fractional shortening with more accuracy than traditional echocardiography, and faster than cardiac MRI!
4D imaging - the next step in the evolution of preclinical echocardiography! Visualize the dynamic motion of the myocardium throughout the cardiac cycle with the 3D geometry of the heart.
4D ultrasound is the perfect solution for cardiac disease models that create abnormalities in the traditional geometric proportions of the heart such as:
- Myocardial infarction - calculate accurate chamber volumes throughout infarct progression
- Congenital heart defects
- Various genetic knockout models
What is 4D Imaging?
3D – High Spatial resolution - seeing the heart from any angle +
EKV – High temporal resolution – seeing the entire cardiac cycle
- Acquire a 3D image at every time-point of the cardiac cycle
- Acquisition in 4D-Mode is intuitive and easy to use!
What can you do with 4D Images?
Combine 4D with Color or Power Doppler on the Vevo F2 for unprecedented visualization of cardiac flow dynamics!
Measurements you can obtain without making any geometric assumptions about the heart:
- Cardiac function (ejection fraction, fractional shortening, cardiac output)
- Area changes
- Volumetric changes
4D Imaging Gallery
4D Publications
TOP PAPER
Commercial 4-dimensional echocardiography for murine heart volumetric evaluation after myocardial infarction
Cardiovascular Ultrasound
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TOP PAPER
Sex differences in the evolution of left ventricle remodeling in rats with severe volume overload
BMC Cardiovascular Disorders
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TOP PAPER
Three-dimensional myocardial strain correlates with murine left ventricular remodelling severity post-infarction
Journal of The Royal Society Interface
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TOP PAPER
Strain Mapping From Four-Dimensional Ultrasound Reveals Complex Remodeling in Dissecting Murine Abdominal Aortic Aneurysms
Journal of Biomechanical Engineering
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TOP PAPER
Accurate and noise insensitive strain mapping enables ultrasound analysis of cardiac function in three dimensions
Journal of Biomechanical Engineering
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TOP PAPER
4D cardiac magnetic resonance imaging, 4D and 2D transthoracic echocardiography: a comparison of in-vivo assessment of ventricular function in rats
Laboratory Animals
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TOP PAPER
Evaluation of a commercial multi-dimensional echocardiography technique for ventricular volumetry in small animals
Cardiovascular Ultrasound
, High-Frequency 4-Dimensional Ultrasound (4DUS): A Reliable Method for Assessing Murine Cardiac Function
Tomography
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