Cardiology
Preclinical Echocardiography for Cardiology Research
Ultra-high frequency (UHF) ultrasound provides superior resolution and will have an incredible impact on cardiovascular research in your animal models.
Perform reliable echocardiography in any animal model for translational cardiovascular research with in vivo resolution down to 30 microns.
Vevo ultrasound imaging platforms provide the best temporal and spatial resolution compared to MRI, conventional ultrasound and CT. The Vevo F2 system can perform preclinical echocardiography in animal models all the way from zebra fish and mice to pigs. Vevo technology has been established as a gold standard technology for mouse cardiac imaging, having been utilized in over 3,000 peer-reviewed publications.
With the Vevo imaging systems you can:
- Perform cardiovascular phenotyping for cardiac structure and function, ideal for stress echo and cardiotoxicity studies
- Image the heart in 4D (with Color or Power Doppler integration)
- Quantify diastolic dysfunction
- Evaluate early signs of cardiac dysfunction with cardiac strain (global or regional synchrony and deformation)
- Perform image-guided cardiac injections
- Monitor full animal physiology while imaging, including body temperature, ECG and respiratory rate
- Assess myocardial oxygen saturation
Cardiac 4D Imaging
Quantify ejection fraction and fractional shortening with more accuracy than traditional echocardiography, and faster than cardiac MRI!
Cardiovascular Workshop
The Heart of the Matter
If you missed this advanced workshop on COVID-19 and other preclinical cardiac disease models, here's your chance to catch up.
Gallery
Cardiac Flow Dynamics and Coronary Artery
Cardiac flow dynamics and Coronary Artery visualized with Color Doppler EKV on the Vevo F2 System.
Apical 4 Chamber View of a Beagle
Apical 4 chamber view of a beagle scanned using a P5-1 transducers on the Vevo F2. Images courtesy of Drs. Kenneth Hoyt and Jay Griffin at Texas A&M University.
Color Doppler of Mouse Aortic Arch
Color Doppler image of an aortic arch in a female mouse, acquired using a UHF57x transducer on the Vevo F2.
Publications
TOP PAPER
Intraluminal gel ultrasound and eco-color doppler: new tools for the study of colorectal cancer in mice.
In vivo (Athens, Greece)
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TOP PAPER
High-frequency ultrasound for in vivo measurement of colon wall thickness in mice.
Ultrasound in medicine & biology
, In Utero dimethadione exposure causes postnatal disruption in cardiac structure and function in the rat
Toxicological Sciences
, Doxorubicin-induced cardiovascular toxicity: a longitudinal evaluation of functional and molecular markers
Cardiovascular Research
, Temporal Progression of Aortic Valve Pathogenesis in a Mouse Model of Osteogenesis Imperfecta
Journal of Cardiovascular Development and Disease
, Characterization of atrial and ventricular remodeling in an improved minimally invasive mouse model of transverse aortic constriction
Journal of Cardiovascular Aging
, Speg interactions that regulate the stability of excitation-contraction coupling protein complexes in triads and dyads
Communications Biology
, Neurovascular hypoxia trajectories assessed by photoacoustic imaging in a murine model of cardiac arrest and resuscitation
IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
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