Theranostics
The Next Generation of Molecular Imaging
Advancing Preclinical Theranostics Research Using High-Frequency Ultrasound and Photoacoustics
Theranostics uses specialized agents that are created and targeted to a specific ligand on a diseased cell. They are injected intravenously and travel to the desired location.
The Ultimate Tool for Cutting-Edge Theranostics Research
Theranostics is a novel field at the forefront of medicine that combines diagnosis and therapy. Expertly-designed agents can be targeted to tumors (or other relevant cells) and visualized using ultrasound or photoacoustics. These agents can then be activated locally to achieve highly specific treatment. This type of personalized medicine is rapidly evolving, with new nanomedicines and theranostic agents being developed continuously.
Vevo F2 LAZR-X ultrasound and photoacoustics can help you with:
- In vitro characterization of novel photoacoustic agents
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Measurement of tissue oxygenation for prediction of theranostic treatment response
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Non-invasive visualization of targeted photoacoustic contrast agents
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Longitudinal imaging and measurement of tumor size in any animal model
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Whole-body imaging for agent/ drug biodistribution studies
Vevo 4 Oncology Web Series
Pancreatic Tumor and Therapy Monitoring
Watch an engaging episode of the Vevo 4 Oncology Web Series, presented by Dr. Srivalleesha Mallidi, and learn more about a powerful, high resolution multi-modal theranostic solution in a pancreatic cancer model. Now available on-demand!
Gallery
Nanoparticle distribution in tumor
3D rendered high-resolution ultrasound (greyscale) and spectrally unmixed photoacoustic (red, blue and gold) image of a subcutaneous tumor showing nanoparticle distribution (yellow) as well as oxygenated (red) and deoxygenated (blue) hemoglobin signal.
Mouse hindlimb showing blood and ICG
3D rendered high-resolution ultrasound (greyscale) and spectrally unmixed photoacoustic (red, blue and green) image of the mouse hindlbimb. The green color indicates ICG dye in the popliteal lymph node after a hindpaw injection, the red color indicated oxygenated hemoglobin and the blue color indicates deoxygenated hemoglobin.