Kidney
Easily Monitor Renal Function in Mice
Monitor renal size and assess function non-invasively and in real-time.
Pulsed-Wave Doppler of the renal artery in a mouse used to calculate blood flow velocities, etc.
With the Vevo imaging systems, you can:
- Calculate renal resistive index and pulsatility index
- Capture accurate 3D volumes
- Evaluate renal microcirculatory flow
- Early detection of cysts, tumors, obstructions, etc.
- Renal biopsy and/or injection
Ultra-high frequency ultrasound is great for preclinical renal models including:
- Chronic kidney disease
- Hypertension
- Polycystic Kidney Disease
- Hydronephrosis
- Renal cancers
Renal vasculature with Color Doppler in a mouse.
Image Guided Injection into the renal cortex in a mouse.
Gallery
Ovary, spleen and kidney
B-mode image of the ovary, spleen and kidney, acquired using a UHF57x transducer on the Vevo F2.
Sagittal View in the Left Kidney
Color Doppler image of the sagittal view in the left kidney, acquired using a UHF57x transducer on the Vevo F2.
Right Liver Lobe and Adrenal Gland
B-mode image of the right liver lobe and adrenal gland, acquired using a UHF57x transducer on the Vevo F2.
Right Kidney Portal System
B-mode image of the right kidney, portal vein, inferior vena cava, acquired using a UHF57x transducer on the Vevo F2.
Right Adrenal Gland of the Mouse
B-mode image of the right adrenal gland of the mouse, acquired using a UHF57x transducer on the Vevo F2.
Renal Artery Flow Measurements
PW Doppler measurements for renal artery flow, acquired using a UHF57x transducer on the Vevo F2.
Publications
TOP PAPER
Photoacoustic imaging of kidney fibrosis for assessing pretransplant organ quality
JCI Insight
,
TOP PAPER
Experimental imaging in orthotopic renal cell carcinoma xenograft models: comparative evaluation of high-resolution 3D ultrasonography, in-vivo micro-CT and 9.4T MRI
Scientific Reports
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TOP PAPER
High Resolution Ultrasonography for Assessment of Renal Cysts in the PCK Rat Model of Autosomal Recessive Polycystic Kidney Disease
Kidney and Blood Pressure Research
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TOP PAPER
Functional polycystin-1 dosage governs autosomal dominant polycystic kidney disease severity
Journal of Clinical Investigation
, Combining immunotherapy with high-dose radiation therapy (HDRT) significantly inhibits tumor growth in a syngeneic mouse model of high-risk neuroblastoma
Heliyon
, Repeated administration of adipose-derived mesenchymal stem cells added on beneficial effects of empagliflozin on protecting renal function in diabetic kidney disease rat
Biomedical Journal
, Tyrosine Kinase Inhibitors Diminish Renal Neoplasms in a Tuberous Sclerosis Model via induction of Apoptosis. Running Title: Inhibiting Mesenchymal Tumors is Therapeutic for LAM and TSC
Molecular Cancer Therapeutics
, Metformin preconditioning protects against myocardial stunning and preserves protein translation in a mouse model of cardiac arrest
Journal of Molecular and Cellular Cardiology Plus
, Effects of Large Extracellular Vesicles from Kidney Cancer Patients on the Growth and Environment of Renal Cell Carcinoma Xenografts in a Mouse Model
Current Issues in Molecular Biology
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