Ultrasonography is a powerful tool to non-invasively monitor in real time the development of the human fetus in utero. Although genetically engineered mice have served as valuable in vivo models to study both embryo implantation and pregnancy progression, …

Background Although cardiac and splenic mononuclear phagocytes (MPs), i.e., monocytes, macro- phages and dendritic cells (DCs), are key contributors to cardiac remodeling after myo- cardial infarction, their role in pressure-overload remodeling is …

Sleep apnea, which is the periodic cessation of breathing during sleep, is a major health problem affecting over 10 million people in the United States and is associated with several sequelae, in- cluding hypertension and stroke. Clinical studies suggest …

4D image of the mouse left ventricle acquired from a parasternal short axis view. A 4D volume was drawn and can be visualized in red. … … 4D Left Ventricular Volume …

High-frequency ultrasound (~20 MHz) techniques were investigated using in vitro and ex vivo models to determine whether alterations in chromatin structure are responsible for ultrasound backscatter changes in biological samples. Acute myeloid leukemia …

The present study focuses on the identification of the gene expression profile of neonatal rat cardiomyocytes (NRVCMs) after dynamic mechanical stretch through microarrays of RNA isolated fromcells stretched for 2, 6 or 24 h. In this analysis,myeloid …

ETHNOPHARMACOLOGICAL RELEVANCE: YiQiFuMai Powder Injection (YQFM), a traditional Chinese medicine prescription re-developed based on Sheng-Mai-San, is a classical and traditional therapeutic for clinical heart failure (HF) and angina. However, its …

Ischemic heart disease resulting from myocardial infarction (MI) is the most prevalent form of heart disease in the United States. Post-MI cardiac remodeling is a multifaceted process that includes activation of fibroblasts and a complex immune response. …

A long non-coding RNA (lncRNA), named myocardial infarction associated transcript (MIAT), has been documented to confer risk of myocardial infarction (MI). The aim of this study is to elucidate the pathophysiological role of MIAT in regulation of cardiac …

4D image of the left atrium in a mouse. … … 4D Image of the Mouse Left Atrium …