Read stories about the exciting work our customers are doing, including preclinical research studies and clinical research studies using Vevo imaging systems.
Dr. Peng Huang presented his work on the development of a clinically translatable cancer theranostic agent at the World Molecular Imaging Conference in Hawaii. This therapy uses a near-infrared (NIR) cyanine dye and human serum albumin (HSA) conjugate for NIRfluorescence/photoacoustic/thermal multimodality imaging and photothermal tumor ablation. Read more.
Dr. Carlton Bates heads an NIH funded research program at the University of Pittsburgh which also benefits from his clinical service as the Chief of Pediatric Nephrology. Many of the mouse models Dr. Bates has generated mimic congenital structural kidney diseases, which are the leading causes of kidney disease in children. Read more.
Terri Swanson, Theresa Tuthill and their team at Pfizer share their story and navigate through some of the translational challenges in developing imaging methods for fibrosis. While fibrosis (tissue scarring) is a normal response to injury, the deposition of connective tissue to form scars challenges the organ to function normally. Read more.
Converting nanoparticles or monomeric compounds into larger supramolecular structures by endogenous or external stimuli is increasingly popular because these materials are useful for imaging and treating diseases. However, conversion of microstructures to nanostructures is less common. Read more.
Dr. Mike Davis' research team at Emory University School of Medicine focuses on various aspects of cardiac regeneration and preservation. His team (part of the joint Biomedical Engineering program at Emory and Georgia Institute of Technology) uses molecular based and biomaterials-based approaches to restore function after cardiac injury. Read more.
Through our collaboration with VisualSonics, we have developed a new protocol for collecting in vivo ECG and respiratory-gated 3D ultrasound volumes in mice in order to visualize complex cardiac motion. Current efforts are focused on using these datasets for subsequent computational flow dynamics and biomechanical modeling. Read more.
The merging of drug therapy and diagnostics to advance personalized medicine is one definition of theranostics. Research in advanced theranostics elevates this concept by merging nanotechnology to benefit drug discovery. Read more.
The unique feature of obtaining tumor structure and functional properties using the Vevo LAZR system enabled us to monitor therapies such as photodynamic therapy and predict tumor recurrence. By precisely monitoring the change in oxygen saturation within the 3D tumor volume, we could predict regions that did not have sufficient therapeutic effect and hence recurred at later time point. Read more.