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Cardiac-specific deletion of the microtubule-binding protein CENP-F causes dilated cardiomyopathy.
Disease models & mechanisms
, Agonist-independent constitutive activity of angiotensin II receptor promotes cardiac remodeling in mice.
Hypertension
, TBX5 drives Scn5a expression to regulate cardiac conduction system function
Journal of Clinical Investigation
, Ryanodine receptor type 2 is required for the development of pressure overload-induced cardiac hypertrophy.
Hypertension
, Cardiac raptor ablation impairs adaptive hypertrophy, alters metabolic gene expression, and causes heart failure in mice.
Circulation
, Cardiomyocyte-specific loss of neurofibromin promotes cardiac hypertrophy and dysfunction.
Circulation research
, Cardiac response to pressure overload in 129S1/SvImJ and C57BL/6J mice: temporal- and background-dependent development of concentric left ventricular hypertrophy
American Journal of Physiology - Heart and Circulatory Physiology
, Accelerated development of pressure overload-induced cardiac hypertrophy and dysfunction in an RyR2-R176Q knockin mouse model.
Hypertension
, Chronic creatine kinase deficiency eventually leads to congestive heart failure, but severity is dependent on genetic background, gender and age.
Basic research in cardiology
, Ginseng Inhibits Cardiomyocyte Hypertrophy and Heart Failure via NHE-1 Inhibition and Attenuation of Calcineurin Activation
Circulation: Heart Failure
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