Blockade of IL-6R prevents preterm birth and adverse neonatal outcomes

Marcelo, Farias-Jofre, Roberto, Romero, Jose, Galaz, Yi, Xu, Derek, Miller, Valeria, Garcia-Flores, Marcia, Arenas-Hernandez, Andrew D, Winters, Bruce A, Berkowitz, Robert H, Podolsky, Yimin, Shen, Tomi, Kanninen, Bogdan, Panaitescu, Catherine R, Glazier, Roger, Pique-Regi, Kevin R, Theis, Nardhy, Gomez-Lopez

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Background Preterm birth preceded by spontaneous preterm labour often occurs in the clinical setting of sterile intra-amniotic inflammation (SIAI), a condition that currently lacks treatment.