Attenuation Coefficients of the Individual Components of the International Electrotechnical Commission Agar Tissue-Mimicking Material

Tissue-mimicking materials (TMMs) are widely used in quality assurance (QA) phantoms to assess the performance of ultrasound scanners. The International Electrotechnical Commission (IEC) defines the acoustic parameters of up to 10 MHz. To manufacture a TMM that closely mimics the acoustical properties of small animal soft tissue at high frequencies, the acoustic properties of each of the individual component ingredients used in the IEC agar-TMM recipe need to be quantified. This study was aimed at evaluating whether the overall attenuation coefficient of the IEC agar-TMM is the linear sum of the attenuation coefficients of each of its ingredients. Eight batches of agar-based materials were manufactured with different combinations of ingredients from the IEC agar-TMM recipe. The percentage concentration of each ingredient used in the individual mixes was identical to that specified in the IEC recipe. The attenuation of each of these batches was measured over the ultrasound frequency range 12–50 MHz, and the attenuation value of the agar component was subtracted from the attenuation values of the other batches. Batch attenuation values, representing the attenuation of individual components within the IEC agar-TMM, were then summated and yielded attenuation values that accurately reproduced the attenuation of the IEC agar-TMM. This information forms a valuable resource for the future development of TMMs with acoustic properties similar to those of soft tissue at high frequencies.