Parametric Map of Oxygen Saturation in an Orthotopic Breast Tumor Model

In this parametric map of oxygen saturation in an orthotopic breast tumor, the breathed oxygen concentration is varied from 100% to 5% back to 100% and the resulting changes in sO2 can be observed in different areas.

Note that the sO2 in the tumor interior does not change appreciably during the breathed oxygen challenge, indicating impaired function of the vasculature there.