Colorectal
Acquire Robust Data to Support Your Colorectal Cancer Research
B-Mode image of the mouse colon with tumor highlighted.
With the Vevo Ultra-High Frequency (UHF) imaging systems you can delineate colon walls, abnormalities, and tumors with high resolution.
How Can Ultra-High Frequency Ultrasound Help with GI research?
- Non-invasive, pre-palpable tumor identification
- 3D volume quantification
- Contrast-enhanced imaging colon and tumor perfusion
- Intestinal motility and inflammation models
RECORDED WEBINAR
Assessment of Murine Colorectal Cancer by UHF Ultrasound using 3D Reconstruction and Non-Linear Contrast Imaging
Presented by Jessica Freeling, MS, VT, LATG, Physiology Core Laboratory Manager, The University of South Dakota
Includes:
• Colorectal cancer (CRC) background information
• Common CRC Mouse Models
• Imaging Modalities and Limitations
Gallery
Orthotopic Pancreatic Tumor
High-resolution ultrasound image of an orthotopic pancreatic tumor outlining anatomy.
Mouse abdominal organs
3D rendered high-resolution ultrasound image of the mouse abdomen showing the kidney, stomach and spleen.
Mouse abdominal organs
3D rendered high-resolution ultrasound (greyscale) and photoacoustic (red) image of the mouse abdomen showing oxygen saturation in the kidney and spleen.
Mouse abdomen
3D rendered high-resolution ultrasound (grey) and photoacoustic (red) image of the whole mouse abdomen showing highly absorbing gut contents overlaid with anatomy as visualized with ultrasound.
Colon Cancer
B-Mode image of the mouse colon in cross-section with presence of a tumor highlighted.
3D Surface Volume of the Mouse Colon with Tumor
Surface view of a 3D volume of a section of mouse colon (in pink) with a tumor (in blue).
Major Structures in the Mouse Abdomen
B-Mode image of the mouse abdomen with all major structures labelled.
Publications
TOP PAPER
Intraluminal gel ultrasound and eco-color doppler: new tools for the study of colorectal cancer in mice.
In vivo (Athens, Greece)
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TOP PAPER
High-frequency ultrasound for in vivo measurement of colon wall thickness in mice.
Ultrasound in medicine & biology
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TOP PAPER
Role of innate immunity and altered intestinal motility in LPS- and MnCl2-induced intestinal intussusception in mice.
American journal of physiology. Gastrointestinal and liver physiology
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TOP PAPER
Assessment and Monitoring Tumor Vascularity With Contrast-Enhanced Ultrasound Maximum Intensity Persistence Imaging
Investigative Radiology
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TOP PAPER
Anti-VEGF therapy reduces intestinal inflammation in Endoglin heterozygous mice subjected to experimental colitis
Angiogenesis
, Antiangiogenic Cancer Therapy : Monitoring with Molecular US and a Clinically Translatable Contrast Purpose : Methods : Results :
Radiology
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