Pterostilbene alleviates abdominal aortic aneurysm via inhibiting macrophage pyroptosis by activating the miR-146a-5p/TRAF6 axis

Huoying, Cai, Lin, Huang, Mingshan, Wang, Ruiming, Liu, Jiacong, Qiu, Yuansen, Qin, Xi, Yao, Shenming, Wang, Chen, Yao, Zuojun, Hu, Yu, Zhou

Food & Function |

Our findings provide evidence that macrophage pyroptosis contributes to the development of AAA and that the activation of the miR-146a/TRAF6 axis by pterostilbene protects against macrophage pyroptosis and AAA formation.