Diet-induced obesity alters the maternal metabolome and early placenta transcriptome and decreases placenta vascularity in the mouse

Tami J, Stuart, Kathleen O ', Neill, David, Condon, Issac, Sasson, Payel, Sen, Yunwei, Xia, Rebecca A, Simmons

Biology of Reproduction |

Obesity in a mouse model leads to alterations in the maternal metabolome and early placenta transcriptome as well as changes in vascularity later in gestation which may provide a mechanism for decreased fetal growth.

https://academic.oup.com/biolreprod/advance-article-abstract/doi/10.1093/biolre/ioy010/4816726